The prices shown on this page were available within the last 20 days for the specified periods and should not be considered the final price offered. Please note that availability and prices are subject to change.

Cheapest time to fly from San Francisco, CA to Panama City

If you’re planning to fly this route soon, keep in mind that the lowest fares are usually available at the end of April. Take advantage of this period to save on your flight tickets and make the most of your trip. Please note that prices may change after your search.

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week: 27 Apr - 3 May

Flights from just $300

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Local currency and cost comparison

TrainLocal, one-way ticket

90%Trains in Panama City are 90% cheaper than in San Francisco, CA.

San Francisco, CA$4.26

Panama City$0.50

MealMid-priced restaurant

60%A meal in Panama City is 60% cheaper than a meal in San Francisco, CA.

San Francisco, CA$35.50

Panama City$14.20

TaxiStandard daytime start rate

40%A taxi fare in Panama City is 40% cheaper than in San Francisco, CA.

San Francisco, CA$5.89

Panama City$3.55

CoffeeRegular cappuccino

34%Coffee in Panama City is 34% cheaper than in San Francisco, CA.

San Francisco, CA$8.03

Panama City$5.27

Exchange rate

1 AUD = 0.71 PAB

1 PAB = 1.43 AUD

Last revised on Fri, 27/03

Distance: 5350 kms

San Francisco, CA airports

San Francisco Intl Airport (SFO)How far from city centre: 18 kms

Panama City airports

Tocumen International Airport (PTY)How far from city centre: 3 kms

Get cheap flights from San Francisco, CA to Panama City

If you plan to fly from San Francisco, CA to Panama City you need to take into consideration that, whatever the reason would be, choosing the right flight is basic to start your journey the best way possible.

Compare a wide range of flights on this route with eDreams. We help you finding the balance between travel time, flexibility, and budget based on what matters most to you.

Flight hubs in San Francisco, CA and Panama City

Your travel experience between San Francisco, CA and Panama City can be greatly influenced by the airports you choose. The departure and arrival airports you select affect not only the total travel time but also the ease of connections and how smoothly you can continue your journey once you land in Panama City.

When searching for flights from San Francisco, CA to Panama City, don’t focus solely on the ticket price. Other aspects that can make your trip more comfortable and convenient include:

Airport location and accessibility, including how far the airport is from Panama City’s city centre or your final destination.
Connections and layovers, especially if your trip involves a stopover and the time between flights is important.
Airport layout and ease of getting around, which is crucial if you have luggage or a tight schedule between flights.

Focusing on these factors can help make your trip from San Francisco, CA to Panama City more seamless and comfortable, allowing you to pick the flight that best suits your travel plans.

San Francisco, CA airport

Most flights from San Francisco, CA to Panama City depart from the main airport of San Francisco, CA, where travellers can enjoy a full range of amenities. From premium shopping to a variety of dining options, the airport has something for everyone. Pick up last-minute souvenirs, browse the latest bestsellers for your flight, catch up on work with free Wi-Fi, or enjoy a relaxed breakfast before take-off to start your journey on the right note.

Panama City airport

Most flights land at Panama City airport. Once you arrive and collect your luggage, it’s a good idea to make sure you have an internet connection on your phone before leaving the airport. If needed, you’ll find nearby stores where you can purchase a local SIM card to help you get around more easily.

Don’t forget to check the transport options from the airport to your accommodation, whether that’s a taxi, public transport or a pre-booked shuttle. Airport staff at the information desk can help you choose the best option.

When is the ideal time to fly from San Francisco, CA to Panama City

Flying from San Francisco, CA to Panama City at different times of the year can offer unique advantages. Travelling during quieter periods often means better seat availability, lower prices, and a more relaxed journey, while busier seasons in Panama City usually provide more flight options and increased frequency.

If you prefer flexibility, fewer crowds, or a slower pace, flying outside peak times is a smart choice. During high-demand periods, planning ahead is essential to secure convenient departure times and avoid last-minute restrictions on this route.

With the eDreams search tool, you can easily compare dates and flight times throughout the year, helping you pick the best time to fly from San Francisco, CA to Panama City based on your travel plans.

Search and book cheap flights from San Francisco, CA to Panama City

When planning flights from San Francisco, CA to Panama City, considering a few practical points can help ensure a smoother booking experience.

Maintain flexibility with travel dates: where possible, adjusting your departure or return by a day or two may result in more competitive fares when flying to Panama City.
Assess airlines and flight schedules carefully: the shortest journey is not always the most cost-effective, and longer routes may offer greater convenience depending on timing.
Review available offers: eDreams Prime provides access to additional discounts on selected flights from San Francisco, CA to Panama City.

Fly from San Francisco, CA to Panama City with eDreams

With eDreams, comparing flights from San Francisco, CA to Panama City is simple and efficient, with transparent prices and practical filters to help you choose the option that best fits your plans.

You can also book accommodation and car hire in one place, making it easy to organise your trip in just a few minutes. From departure to arrival, everything you need to plan your journey is brought together in a smooth, end-to-end experience. Booking your flight from San Francisco, CA to Panama City with eDreams has never been more straightforward.

FAQs about flights from San Francisco, CA to Panama City

Can I get a flexible ticket for my trip from San Francisco, CA to Panama City?

At eDreams, we want your trip to run smoothly. Whether your flight gets canned or Panama suddenly changes travel rules, you’ll be covered. Flight cancelled? No dramas! With our flexible ticket option, you can rebook your San Francisco, CA to Panama City flight with no change fee, or grab a full refund.

What’s the typical cost of a ticket from San Francisco, CA to Panama City?

The average airfare for flights from San Francisco, CA to Panama City is about $1,018. Prices can shift depending on the season and how early you lock in your tickets.

How do I score the cheapest flights from San Francisco, CA to Panama City with eDreams?

Right now, the lowest fare from San Francisco, CA to Panama City is $ 289. Thanks to our clever tech, we line up the top flight options, mixing and matching routes, airlines, and timetables to nail both value and convenience.

Is Panama City more expensive than San Francisco, CA?

In Panama City, taxis are about 40% pricier, costing roughly 3.55 AUD, compared with San Francisco, CA where a ride averages 5.89 AUD.

When it comes to getting around, the average cab fare in Panama City is 3.55 AUD, pretty similar to San Francisco, CA.

Cab rides in Panama City can be about 40% cheaper, averaging 3.55 AUD, compared to 5.89 AUD in San Francisco, CA.

Catching the train in Panama City will cost you about 88% more, sitting at 0.50 AUD compared with 4.26 AUD in San Francisco, CA.

Train tickets are much the same in Panama City and San Francisco, CA, averaging 0.50 AUD.

Fares are roughly 88% cheaper in Panama City, with tickets priced at 0.50 AUD compared to 4.26 AUD in San Francisco, CA.

In some cases, eating out in Panama City will sting you about 60% more, with average meals at 14.20 AUD, compared with 35.50 AUD in San Francisco, CA.

As for lunch, expect to pay about 14.20 AUD in both Panama City and San Francisco, CA.

Meals in Panama City cost around 14.20 AUD, which is about 60% less than the 35.50 AUD you’d fork out in San Francisco, CA.

A coffee will set you back about 34% more in Panama City, averaging 5.27 AUD, while in San Francisco, CA it’s around 8.03 AUD.

Coffee prices are pretty much on par in both San Francisco, CA and Panama City, averaging about 5.27 AUD.

Coffee is roughly 34% cheaper in Panama City, coming in at 5.27 AUD, compared to 8.03 AUD in San Francisco, CA.

What’s the average flight time from San Francisco, CA to Panama City?

A standard flight between San Francisco, CA and Panama City takes around 7 h and 20 m, covering about 5,349.96 km. This includes both direct flights and connections.

How does the weather in Panama City compare with San Francisco, CA?

In summer, San Francisco, CA usually sees highs around 16.62 ºC. Over in Panama City, temps sit around 27.28 ºC. In winter, Panama City averages about 26.28 ºC, while San Francisco, CA hovers near 11.23 ºC.

Which airports connect San Francisco, CA with Panama City?

The main route linking San Francisco, CA with Panama City is between San Francisco International Airport (SFO) and Tocumen International Airport(PTY). This leg is operated by the following airlines:

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